Kianoush Kashani

• Practical Steps to Train (and Become) an AI-Era Physician
  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology

  Rolando Claure-Del Granado Speaker Practical Steps to Train (and Become) an AI-Era PhysicianPrecision Solute Control and Dynamic Dosing with CRRTSocial Determinants of Health and Acute Kidney Injury

• Optimizing CRRT Delivery for Improved Outcomes: Toward Precision AKI Care
  Jay Koyner Speaker Special lecture: 2026 KDIGO AKI Guideline UpdateTargeting Persistent AKI and Promoting Recovery
• From Data to Decision: Advancing Quality and Outcomes in CRRT through Digital Innovation
  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology
• Panel Discussion

• Chair's Opening: Framing AI + Big Data Along the AKI/CRRT Care Pathway
  Chia-Chao Wu Speaker

  Chin-Chung Tseng Speaker
• Korean Big-Data Experience in AKI and CRRT Outcomes
  Sejoong Kim Speaker Korean Big-Data Experience in AKI and CRRT OutcomesSouth Korea has established a robust nationwide health data infrastructure, enabling large-scale analyses of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT). Leveraging the Health Insurance Review and Assessment Service (HIRA) and National Health Insurance Service (NHIS) databases, Korean researchers have characterized AKI incidence, risk factors, and short- and long-term outcomes across diverse clinical settings. Studies utilizing CRRT data have identified predictors of mortality, renal recovery, and progression to chronic kidney disease. These big-data approaches provide critical real-world evidence, informing clinical practice and guiding future interventional strategies in critically ill patients with AKI.Precision Volume Management in CRRT: Insights from Bioimpedance and BiomarkersOptimal fluid balance is critical in critically ill patients undergoing continuous renal replacement therapy (CRRT), yet accurate volume assessment remains challenging. Bioimpedance analysis (BIA) offers a non-invasive, objective method to quantify fluid overload and guide individualized ultrafiltration targets. Complementing BIA, emerging biomarkers provide dynamic, real-time insights into volume status and end-organ perfusion. Integrating these tools into a precision medicine framework may optimize fluid removal strategies, reduce complications, and improve survival outcomes in CRRT-dependent patients. Prospective validation of this combined approach is warranted.
• Deep Learning ECG as a Non-Invasive Window into Kidney Function and Electrolytes
  Chin Lin Speaker Deep Learning Electrocardiography as a Non-Invasive Window into Kidney Function and Electrolyte DisturbancesRecent advances in deep learning have transformed the standard 12-lead electrocardiogram (ECG) from a tool for rhythm interpretation into a scalable physiologic sensor capable of detecting systemic disease. In this lecture, we will review the development and clinical translation of AI-enabled ECG models for dyskalemia detection and renal-function estimation. Using large real-world cohorts, convolutional and attention-based neural networks have demonstrated high accuracy for identifying moderate-to-severe hyperkalemia and hypokalemia directly from ECG waveforms, frequently preceding laboratory confirmation and outperforming clinician interpretation. Beyond electrolyte detection, AI-ECG signatures were also associated with adverse outcomes, cardiovascular risk, and future chronic kidney disease progression, even among patients with apparently normal laboratory findings. We will further discuss pragmatic deployment studies showing how real-time AI-ECG alerts integrated into emergency department workflows can accelerate treatment decisions for life-threatening hyperkalemia. Finally, the talk will address how signal-based AI can complement EHR-based prediction models in critical-care nephrology, including issues of interpretability, calibration drift, implementation, and multimodal foundation-model integration.
• AI in Critical Care Nephrology — State of the Art and the Path from Algorithm to Bedside
  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology
• Precision Sepsis-AKI — Biomarkers, AI and Phenotyping in the Asia-Pacific
  Nattachai Srisawat Speaker Precision Sepsis-AKI — Biomarkers, AI and Phenotyping in the Asia-PacificTiming of DialysisAcute PD vs Acute HD: Which Is the Right Choice?
• Panel Discussion
  Chin Lin Speaker Deep Learning Electrocardiography as a Non-Invasive Window into Kidney Function and Electrolyte DisturbancesRecent advances in deep learning have transformed the standard 12-lead electrocardiogram (ECG) from a tool for rhythm interpretation into a scalable physiologic sensor capable of detecting systemic disease. In this lecture, we will review the development and clinical translation of AI-enabled ECG models for dyskalemia detection and renal-function estimation. Using large real-world cohorts, convolutional and attention-based neural networks have demonstrated high accuracy for identifying moderate-to-severe hyperkalemia and hypokalemia directly from ECG waveforms, frequently preceding laboratory confirmation and outperforming clinician interpretation. Beyond electrolyte detection, AI-ECG signatures were also associated with adverse outcomes, cardiovascular risk, and future chronic kidney disease progression, even among patients with apparently normal laboratory findings. We will further discuss pragmatic deployment studies showing how real-time AI-ECG alerts integrated into emergency department workflows can accelerate treatment decisions for life-threatening hyperkalemia. Finally, the talk will address how signal-based AI can complement EHR-based prediction models in critical-care nephrology, including issues of interpretability, calibration drift, implementation, and multimodal foundation-model integration.

  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology

  Nattachai Srisawat Speaker Precision Sepsis-AKI — Biomarkers, AI and Phenotyping in the Asia-PacificTiming of DialysisAcute PD vs Acute HD: Which Is the Right Choice?

  Sejoong Kim Speaker Korean Big-Data Experience in AKI and CRRT OutcomesSouth Korea has established a robust nationwide health data infrastructure, enabling large-scale analyses of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT). Leveraging the Health Insurance Review and Assessment Service (HIRA) and National Health Insurance Service (NHIS) databases, Korean researchers have characterized AKI incidence, risk factors, and short- and long-term outcomes across diverse clinical settings. Studies utilizing CRRT data have identified predictors of mortality, renal recovery, and progression to chronic kidney disease. These big-data approaches provide critical real-world evidence, informing clinical practice and guiding future interventional strategies in critically ill patients with AKI.Precision Volume Management in CRRT: Insights from Bioimpedance and BiomarkersOptimal fluid balance is critical in critically ill patients undergoing continuous renal replacement therapy (CRRT), yet accurate volume assessment remains challenging. Bioimpedance analysis (BIA) offers a non-invasive, objective method to quantify fluid overload and guide individualized ultrafiltration targets. Complementing BIA, emerging biomarkers provide dynamic, real-time insights into volume status and end-organ perfusion. Integrating these tools into a precision medicine framework may optimize fluid removal strategies, reduce complications, and improve survival outcomes in CRRT-dependent patients. Prospective validation of this combined approach is warranted.
• Chair's Synthesis and Take-Home Points
  Chia-Chao Wu Speaker

  Chin-Chung Tseng Speaker

• Trajectories of Critical Illness – Defining Endotypes from Routine Data
  John Prowle Speaker Trajectories of Critical Illness – Defining Endotypes from Routine DataCritical illness is a heterogeneous syndrome characterized by diverse clinical trajectories and variable responses to treatment. Defining biologically and clinically meaningful endotypes using routinely collected healthcare data offers an opportunity to improve risk stratification, prognostication, and personalized therapeutic strategies, enabling earlier intervention, enhanced clinical decision-making, and precision medicine in critical care. In particular the transition from acute to persistent critical illness represents a pivotal phase in intensive care, marked by a shift from the initial disease insult to prolonged organ dysfunction driven by complex host responses. Early identification of patients at risk of this transition remains a major clinical challenge and opportunity.Dynamic Prescription of CRRT Ready for Prime TimeContinuous renal replacement therapy (CRRT) has evolved from a standardized supportive therapy to a platform for precision critical care. Increasing evidence suggests that fixed prescriptions fail to accommodate the dynamic physiological changes encountered during critical illness, resulting in suboptimal solute clearance, fluid management, and metabolic control. Dynamic prescription integrates evolving haemodynamic status, fluid balance, acid–base homeostasis, electrolyte disturbances, and recovery trajectories to optimize therapy delivery while minimizing complications and treatment interruptions. This paradigm supports individualized kidney support rather than protocol-driven care. Emerging decision-support systems and data-driven algorithms have the potential to transform CRRT into a responsive, patient-centred intervention, improving kidney recovery, organ support, and outcomes in critically ill patients. Adapting CRRT for patients with Electrolyte and acid-base disordersContinuous renal replacement therapy (CRRT) is uniquely positioned to provide precise correction of complex electrolyte and acid–base disturbances in critically ill patients. Beyond kidney support, modern CRRT prescriptions can be individualized to account for the severity and evolution of dysnatremia, dyskalemia, calcium disorders, and metabolic acidosis or alkalosis. Customization of dialysate and replacement fluid composition, treatment dose, buffer delivery, and regional citrate anticoagulation enables controlled correction while minimizing the risks of metabolic complications. Dynamic prescription based on serial biochemical monitoring and changing clinical physiology can be embedded into treatment protocols, facilitating safe correction of sodium, potassium, calcium, and bicarbonate abnormalities while optimizing organ support and improving outcomes in critically ill patients. Extracorporeal Therapies in Trauma, Burns and Cerebral OedemaExtracorporeal therapies (ECTs) are an important adjunct in the management of critically ill patients with severe trauma, major burns, and brain injuries. Acute kidney injury, systemic inflammation, rhabdomyolysis, and profound fluid and electrolyte disturbances frequently complicate these conditions, necessitating timely organ support. Continuous kidney replacement therapy (CKRT) provides effective management of metabolic derangements while enabling precise fluid balance in hemodynamically unstable patients. In trauma and burns, ECTs may facilitate the clearance of myoglobin in severe rhabdomyolysis, support fluid management during resuscitation, and could enable removal of damage or pathogen associated molecular patterns mediating multiorgan failure. In patients with cerebral edema, CKRT offers gradual osmotic control and minimizes intracranial pressure fluctuations compared with intermittent dialysis, making it the preferred modality when kidney replacement therapy is required. We will review current evidence, practical considerations, and emerging extracorporeal strategies, highlighting their role in improving physiological stability and supporting recovery in critically ill patients.
• MultimodalIndividualized Hemodynamic Management
  Zsolt Molnár Speaker
• Utility of Lung Ultrasound, VEXUS and Bioimpedance Analysis in Volume Assessment During RRT
  Nuttha Lumlertgul Speaker Solution and Fluid BalanceUtility of Lung Ultrasound, VEXUS and Bioimpedance Analysis in Volume Assessment During RRT Personalized Fluid Management with CRRT
• Immune Disorders of AKI Patients Following Various Types of Injuries ?
  Thomas Rimmele Speaker Managing Patients with Sepsis: modifying the course with ECOSImmune Disorders of AKI Patients Following Various Types of InjuriesHow do I use Hemadsorption in My Practice
• Late Breaking Clinical Trials or Critical Care Nephrology: Literature Review
  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology
• Q & A

• AI in the ICU or Chat GPT Applications in Critical Care Nephrology
  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology
• Fluid Balance Reimagined: Hemodynamic Monitoring and Ultrafiltration Precision
  Ravindra Mehta Speaker
• Precision Volume Management in CRRT: Insights from Bioimpedance and Biomarkers
  Sejoong Kim Speaker Korean Big-Data Experience in AKI and CRRT OutcomesSouth Korea has established a robust nationwide health data infrastructure, enabling large-scale analyses of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT). Leveraging the Health Insurance Review and Assessment Service (HIRA) and National Health Insurance Service (NHIS) databases, Korean researchers have characterized AKI incidence, risk factors, and short- and long-term outcomes across diverse clinical settings. Studies utilizing CRRT data have identified predictors of mortality, renal recovery, and progression to chronic kidney disease. These big-data approaches provide critical real-world evidence, informing clinical practice and guiding future interventional strategies in critically ill patients with AKI.Precision Volume Management in CRRT: Insights from Bioimpedance and BiomarkersOptimal fluid balance is critical in critically ill patients undergoing continuous renal replacement therapy (CRRT), yet accurate volume assessment remains challenging. Bioimpedance analysis (BIA) offers a non-invasive, objective method to quantify fluid overload and guide individualized ultrafiltration targets. Complementing BIA, emerging biomarkers provide dynamic, real-time insights into volume status and end-organ perfusion. Integrating these tools into a precision medicine framework may optimize fluid removal strategies, reduce complications, and improve survival outcomes in CRRT-dependent patients. Prospective validation of this combined approach is warranted.
• Dynamic Prescription of CRRT Ready for Prime Time
  John Prowle Speaker Trajectories of Critical Illness – Defining Endotypes from Routine DataCritical illness is a heterogeneous syndrome characterized by diverse clinical trajectories and variable responses to treatment. Defining biologically and clinically meaningful endotypes using routinely collected healthcare data offers an opportunity to improve risk stratification, prognostication, and personalized therapeutic strategies, enabling earlier intervention, enhanced clinical decision-making, and precision medicine in critical care. In particular the transition from acute to persistent critical illness represents a pivotal phase in intensive care, marked by a shift from the initial disease insult to prolonged organ dysfunction driven by complex host responses. Early identification of patients at risk of this transition remains a major clinical challenge and opportunity.Dynamic Prescription of CRRT Ready for Prime TimeContinuous renal replacement therapy (CRRT) has evolved from a standardized supportive therapy to a platform for precision critical care. Increasing evidence suggests that fixed prescriptions fail to accommodate the dynamic physiological changes encountered during critical illness, resulting in suboptimal solute clearance, fluid management, and metabolic control. Dynamic prescription integrates evolving haemodynamic status, fluid balance, acid–base homeostasis, electrolyte disturbances, and recovery trajectories to optimize therapy delivery while minimizing complications and treatment interruptions. This paradigm supports individualized kidney support rather than protocol-driven care. Emerging decision-support systems and data-driven algorithms have the potential to transform CRRT into a responsive, patient-centred intervention, improving kidney recovery, organ support, and outcomes in critically ill patients. Adapting CRRT for patients with Electrolyte and acid-base disordersContinuous renal replacement therapy (CRRT) is uniquely positioned to provide precise correction of complex electrolyte and acid–base disturbances in critically ill patients. Beyond kidney support, modern CRRT prescriptions can be individualized to account for the severity and evolution of dysnatremia, dyskalemia, calcium disorders, and metabolic acidosis or alkalosis. Customization of dialysate and replacement fluid composition, treatment dose, buffer delivery, and regional citrate anticoagulation enables controlled correction while minimizing the risks of metabolic complications. Dynamic prescription based on serial biochemical monitoring and changing clinical physiology can be embedded into treatment protocols, facilitating safe correction of sodium, potassium, calcium, and bicarbonate abnormalities while optimizing organ support and improving outcomes in critically ill patients. Extracorporeal Therapies in Trauma, Burns and Cerebral OedemaExtracorporeal therapies (ECTs) are an important adjunct in the management of critically ill patients with severe trauma, major burns, and brain injuries. Acute kidney injury, systemic inflammation, rhabdomyolysis, and profound fluid and electrolyte disturbances frequently complicate these conditions, necessitating timely organ support. Continuous kidney replacement therapy (CKRT) provides effective management of metabolic derangements while enabling precise fluid balance in hemodynamically unstable patients. In trauma and burns, ECTs may facilitate the clearance of myoglobin in severe rhabdomyolysis, support fluid management during resuscitation, and could enable removal of damage or pathogen associated molecular patterns mediating multiorgan failure. In patients with cerebral edema, CKRT offers gradual osmotic control and minimizes intracranial pressure fluctuations compared with intermittent dialysis, making it the preferred modality when kidney replacement therapy is required. We will review current evidence, practical considerations, and emerging extracorporeal strategies, highlighting their role in improving physiological stability and supporting recovery in critically ill patients.
• Bicarbonate in AKI: Use and Misuse
  Lui Forni Speaker Sepsis Associated AKIBicarbonate therapy for AKI or Bicarbonate in AKI: Use and MisuseAdapting CRRT for Patients with Electrolyte and Acid-Base Disorders
• De-escalating and Transitioning RRT: Best Practices
  Kathleen Liu Speaker How do I Manage Patients with Combined Kidney and Liver FailureKidney-Ventilator Interactions and Kidney Protective Ventilation /or Lung and Kidney CrosstalkHow do I care for the Patient with ARDS and AKIDe-escalating and Transitioning RRT: Best Practices
• Q & A