Jei-Wen Chang

Professor Jei-Wen Chang, MD, PhD is a Professor of Pediatrics at National Yang Ming Chiao Tung University (NYCU) and Chief of the Division of General Pediatrics at Taipei Veterans General Hospital (Taipei VGH), Taiwan. She also serves as Vice Chair of the Department of Medicine and Chief of the Division of Pediatrics at the NYCU School of Medicine. Professor Chang earned her MD and PhD from National Yang Ming University and completed research training at the University of Miami Kidney Transplant Center and Imperial College London. Her clinical and research interests focus on pediatric nephrology, particularly pediatric kidney transplantation, chronic kidney disease, dialysis, congenital anomalies of the kidney and urinary tract (CAKUT), inherited kidney diseases, and precision medicine. She has established one of Taiwan's leading pediatric kidney transplant programs, achieving excellent graft outcomes, and has pioneered the application of genomic medicine in children with rare kidney diseases. Her research spans pediatric kidney transplantation, transplant-related complications, pediatric urology, autoimmune kidney diseases, and nationwide population-based studies aimed at improving outcomes for children with kidney and immune-mediated disorders.

20th September 2026 Sunday

Time Session
10:45
12:30
New Horizons in Neonatal & Pediatric AKI-AKD Continuum
Min-Hua Tseng Moderator
Shotaro Matsumoto Moderator The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
  • The Missing Link: Navigating the Acute Kidney Disease (AKD) Window and Preventing CKD
    Jei-Wen Chang Speaker The Missing Link: Navigating the Acute Kidney Disease (AKD) Window and Preventing CKDThe paradigm of acute kidney injury (AKI) has shifted dramatically over the past decade. Once regarded as a transient event, AKI is now recognized as the initiating step in a continuum that progresses through acute kidney disease (AKD) to chronic kidney disease (CKD). Representing the "missing link" in this spectrum, AKD—defined as persistent kidney dysfunction or injury lasting between 7 and 90 days after AKI—constitutes a critical, modifiable window during which timely intervention may interrupt disease progression and prevent irreversible kidney damage. This continuum is particularly pivotal in neonates and children. The developing kidney possesses unique developmental vulnerabilities, including incomplete nephrogenesis, reduced nephron endowment, and functional immaturity. Conditions such as prematurity, congenital anomalies of the kidney and urinary tract (CAKUT), hypoxic-ischemic injury, sepsis, congenital heart disease, and nephrotoxin exposure further compound the risk of maladaptive repair and incomplete recovery. Even following apparent clinical recovery, maladaptive repair and interstitial fibrosis may persist, increasing the lifelong risk of CKD, hypertension, and cardiovascular disease. This lecture will review the evolving concepts, epidemiology, and pathophysiological mechanisms of the AKI–AKD–CKD continuum, with an emphasis on neonatal and pediatric populations. Emerging biomarkers for the early detection of persistent kidney injury, risk stratification, and practical post-AKI management—including nephrotoxin stewardship, structured surveillance, and multidisciplinary follow-up—will be discussed. Recognizing AKD as a distinct clinical entity shifts the focus from treating AKI to promoting kidney recovery, offering a unique opportunity to preserve long-term kidney health and prevent CKD.
    Shotaro Matsumoto Moderator The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
  • Spotlight on Neonatal AKI: The AWAKEN Criteria, Unique Phenotypes, and Genetic Insights
    Chih-Chia Chen Speaker Spotlight on Neonatal AKI: The AWAKEN Criteria, Unique Phenotypes, and Genetic Insights
    Shotaro Matsumoto Moderator The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
  • The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in Pediatrics
    Shotaro Matsumoto Speaker The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
    Min-Hua Tseng Moderator
  • Beyond Renal Replacement: Advanced Extracorporeal Blood Purification in Pediatric Sepsis
    I-Jung Tsai Speaker Beyond Renal Replacement: Advanced Extracorporeal Blood Purification in Pediatric Sepsis
    Min-Hua Tseng Moderator
  • Q&A
Room 4