Programme

• Targeting Persistent AKI and Promoting Recovery
  Chi-yuan Hsu Speaker Targeting Persistent AKI and Promoting RecoveryDoes Mild to Moderate AKI Actually Cause CKD?

  Jay Koyner Speaker Special lecture: 2026 KDIGO AKI Guideline UpdateTargeting Persistent AKI and Promoting Recovery

• How Do I Use Hemadsorption in My Practice
  Claudio Ronco Speaker Hemoadsorption in the ICUSpecial lecture: 50 years of CRRT: a journey through innovationRole of Renal Functional Reserve on AKI risk and RecoveryHow do I use Hemadsorption in My PracticeManaging the Heart Failure Patient With Worsening Renal Function (WRF)

  Thomas Rimmele Speaker Managing Patients with Sepsis: modifying the course with ECOSImmune Disorders of AKI Patients Following Various Types of InjuriesHow do I use Hemadsorption in My Practice

• Timing of Dialysis
  Nattachai Srisawat Speaker Precision Sepsis-AKI — Biomarkers, AI and Phenotyping in the Asia-PacificTiming of DialysisAcute PD vs Acute HD: Which Is the Right Choice?

  Ravindra Mehta Speaker

• AI in the ICU or Chat GPT Applications in Critical Care Nephrology
  Kianoush Kashani Speaker Practical Steps to Train (and Become) an AI-Era PhysicianAI in Critical Care Nephrology — State of the Art and the Path from Algorithm to BedsideLate breaking clinical trials or Critical Care Nephrology: Literature Review AI in the ICU or Chat GPT Applications in Critical Care Nephrology
• Fluid Balance Reimagined: Hemodynamic Monitoring and Ultrafiltration Precision
  Ravindra Mehta Speaker
• Precision Volume Management in CRRT: Insights from Bioimpedance and Biomarkers
  Sejoong Kim Speaker Korean Big-Data Experience in AKI and CRRT OutcomesSouth Korea has established a robust nationwide health data infrastructure, enabling large-scale analyses of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT). Leveraging the Health Insurance Review and Assessment Service (HIRA) and National Health Insurance Service (NHIS) databases, Korean researchers have characterized AKI incidence, risk factors, and short- and long-term outcomes across diverse clinical settings. Studies utilizing CRRT data have identified predictors of mortality, renal recovery, and progression to chronic kidney disease. These big-data approaches provide critical real-world evidence, informing clinical practice and guiding future interventional strategies in critically ill patients with AKI.Precision Volume Management in CRRT: Insights from Bioimpedance and BiomarkersOptimal fluid balance is critical in critically ill patients undergoing continuous renal replacement therapy (CRRT), yet accurate volume assessment remains challenging. Bioimpedance analysis (BIA) offers a non-invasive, objective method to quantify fluid overload and guide individualized ultrafiltration targets. Complementing BIA, emerging biomarkers provide dynamic, real-time insights into volume status and end-organ perfusion. Integrating these tools into a precision medicine framework may optimize fluid removal strategies, reduce complications, and improve survival outcomes in CRRT-dependent patients. Prospective validation of this combined approach is warranted.
• Dynamic Prescription of CRRT Ready for Prime Time
  John Prowle Speaker Trajectories of Critical Illness – Defining Endotypes from Routine DataDynamic Prescription of CRRT Ready for Prime TimeAdapting CRRT for patients with Electrolyte and acid-base disordersExtracorporeal Therapies in Trauma, Burns and Cerebral Edema
• Bicarbonate in AKI: Use and Misuse
  Lui Forni Speaker Sepsis Associated AKIBicarbonate therapy for AKI or Bicarbonate in AKI: Use and MisuseAdapting CRRT for Patients with Electrolyte and Acid-Base Disorders
• De-escalating and Transitioning RRT: Best Practices
  Kathleen Liu Speaker How do I Manage Patients with Combined Kidney and Liver FailureKidney-Ventilator Interactions and Kidney Protective Ventilation /or Lung and Kidney CrosstalkHow do I care for the Patient with ARDS and AKIDe-escalating and Transitioning RRT: Best Practices
• Q & A

• Advancing ECCO2R Therapy: Lessons from Vietnam for the Asia-Pacific Region
  Do Ngoc Son Speaker Advancing ECCO₂R Therapy: Lessons from Vietnam for the Asia-Pacific Region

  Te-Chao Fang Moderator
• The Application of Novel Renal Biomarkers in Clinical and Environmental Nephrology
  Kai-Fan Tsai Speaker

  Te-Chao Fang Moderator
• Coffee break
• Developing Next-Generation Dialysis Technologies for Acute Kidney Care and Disaster Preparedness
  Kenichi Kokubo Speaker Developing Next-Generation Dialysis Technologies for Acute Kidney Care and Disaster Preparedness

  Shih-Hua Lin Moderator

  Chia-Te Liao Moderator
• Blood Purification in Disasters: Japan’s Evolving Approach to Hospital Resilience, DMAT Coordination, and ICU-Based Renal Support
  Takeshi Moriguchi Speaker Blood Purification in Disasters: Japan’s Evolving Approach to Hospital Resilience, DMAT Coordination, and ICU-Based Renal Support[Background] Disasters markedly increase the incidence of acute kidney injury (AKI) while simultaneously disrupting the critical lifelines required to deliver renal support. In Japan, most maintenance dialysis patients receive treatment in outpatient clinics rather than large hospitals. During major disasters, including the Noto Peninsula earthquake, the status of affected dialysis facilities and the number of patients requiring treatment were rapidly assessed. Dialysis networks allocated patients based on receiving capacity and arranged transfers outside the affected area when necessary. This demonstrates that disaster renal care relies as much on logistics, information sharing, and regional coordination as it does on dialysis techniques. [Acute Care & Resource Requirements] Acute renal replacement therapy for critically ill patients is typically provided in large hospitals and consumes substantial resources. Patients presenting with crush syndrome, rhabdomyolysis, trauma, shock, sepsis, heat-related illness, or multiple organ failure may require intermittent hemodialysis (IHD), prolonged intermittent renal replacement therapy (PIRRT), or continuous renal replacement therapy (CRRT). These therapies strictly depend on electricity, water, replacement fluids, circuits, filters, catheters, anticoagulants, and trained medical staff. Prompt diagnosis, triage, and timely transfer to hospitals capable of acute blood purification are essential to effective disaster response. [Systems & DMAT Integration] This lecture highlights Japan’s evolving approach to disaster blood purification, developed through repeated experiences with earthquakes, tsunamis, floods, and other emergencies. Particular emphasis is placed on Disaster Base Hospitals, which are expected to maintain emergency functions through earthquake-resistant infrastructure, backup power, water supplies, medical stockpiles, robust communication networks, business continuity planning (BCP), and specialized personnel. Additionally, the role of Disaster Medical Assistance Teams (DMAT) will be discussed in evaluating hospital capabilities, supporting affected facilities, coordinating patient transport, and bridging field medicine with ICU-capable facilities. [Conclusions] From an ICU perspective, disaster blood purification requires a delicate balance between physiological benefit and logistical feasibility. Continuous therapies (CRRT) should be reserved for hemodynamically unstable patients requiring ongoing support, whereas intermittent therapies (IHD/PIRRT) are preferable when rapid correction of hyperkalemia or acidosis is needed, or when resources are limited. Ultimately, blood purification in disasters is a system-dependent form of organ support: a CRRT machine is only as strong as the hospital and regional lifelines behind it.

  Shih-Hua Lin Moderator

  Chia-Te Liao Moderator
• Closing Remarks
  Lung-Chih Li Speaker

  Shih-Hua Lin Moderator

  Chia-Te Liao Moderator

• Micronutrient Strategy in Critically Ill AKI Patients: Balancing Oxidative Stress, Inflammation, and CRRT Losses
  Yin-Yi Han Speaker Micronutrient Strategy in Critically Ill AKI Patients: Balancing Oxidative Stress, Inflammation, and CRRT LossesAcute kidney injury is common in critically ill patients and is frequently accompanied by systemic inflammation, oxidative stress, mitochondrial dysfunction, immune dysregulation, and metabolic instability. In this context, micronutrients are not merely supportive supplements; they serve as essential cofactors for antioxidant defense, immune competence, endothelial integrity, energy metabolism, and tissue repair. However, micronutrient management in critically ill patients with AKI is challenging because of increased requirements, difficulty in assessing deficiency, impaired renal clearance, and substantial losses during continuous renal replacement therapy (CRRT). This lecture will discuss practical micronutrient strategies for critically ill patients with AKI, focusing on key nutrients such as thiamine, vitamin C, vitamin D, selenium, zinc, copper, and other trace elements. Their biological roles, potential CRRT-related losses, clinical relevance, and safety considerations will be reviewed. Based on current evidence and clinical experience, a risk-adapted, phase-based approach will be proposed to balance deficiency correction, metabolic resilience, and avoidance of excessive supplementation in this vulnerable population.
• Energy and Protein Prescription in AKI During CRRT: Precision Nutrition Support vs Predictive Estimation
  Chih-Yi Hsu Speaker Energy and Protein Prescription in AKI During CRRT: Precision Nutrition Support vs Predictive Estimation急性腎損傷（AKI）合併連續性腎臟替代治療（CRRT）患者常處於高度代謝壓力與蛋白質分解狀態，且CRRT過程中會增加胺基酸、葡萄糖及微量營養素流失，使能量與蛋白質需求更加複雜。傳統以預測公式進行營養處方，於此族群可能產生顯著誤差，無法反映個別病人的動態代謝變化。近年來，精準營養支持概念逐漸受到重視，強調依據間接熱量測定、氮平衡及臨床病程進行個別化調整。本演講將比較預測估算與精準營養策略於CRRT病人中的應用，並探討其臨床可行性與實務整合，以提升重症營養照護品質。
• Coffee Break
• Preoperative Metabolic Optimization: Can Amino Acid Supplementation Reduce Postoperative AKI?
  Tsui-Yin Tung Speaker Preoperative Metabolic Optimization: Can Amino Acid Supplementation Reduce Postoperative AKI?研究與統合分析證實，手術中靜脈輸注胺基酸顯著降低AKI風險。機制為激發腎儲備功能、優化腎臟灌注。此方案安全且具成本效益，縮短住院天數。雖未降低死亡率，仍是Level 1實證的可行方式。
• Nutrition in Hepato-Renal Syndrome: Protein Restriction, Keto-Analogues, and Metabolic Modulation
  Hong Kai-Yi Speaker
• Post-AKI Nutritional Recovery: Preventing Sarcopenia and Slowing AKI-to-CKD Transition
  Shu-Tzu Chen Speaker Post-AKI Nutritional Recovery: Preventing Sarcopenia and Slowing AKI-to-CKD TransitionIt is a misconception that patients recovering from acute kidney injury should avoid a high-protein diet that may increase the risk of sarcopenia. However, this concept is not supported by current evidence. Adequate protein intake helps preserve lean body mass by reducing muscle protein breakdown, but high protein intake alone does not stimulate muscle hypertrophy. Excessive protein consumption may only increase nitrogenous waste production and impose an unnecessary metabolic burden on the recovering kidneys. The most effective strategy for increasing muscle mass is resistance exercise combined with appropriate nutritional supplement. Carbohydrate intake before exercise helps reduce muscle protein breakdown, while adequate carbohydrate with a small amount of protein after exercise effectively stimulates muscle protein synthesis and promotes muscle growth. This lecture will review the physiological mechanisms underlying skeletal muscle hypertrophy and discuss evidence-based exercise and nutritional strategies for the prevention and treatment of sarcopenia in patients with kidney disease, with particular emphasis on those recovering from acute kidney injury. 若需中文摘要 如下 急性腎損傷恢復期的病人不適合攝取高蛋白質飲食可能導致肌少症發生是錯誤的觀念，因為增加蛋白質攝取才能增加肌肉量避免肌少症發生並不正確。足夠的蛋白質可避免肌肉分解，但不會增加肌肉量。增加肌肉量不需要大量的蛋白質，過多的蛋白質只會產生較多的含氮廢物增加腎臟負擔。增加肌肉量需要阻力運動與運動前、後正確的營養補充;運動前補充糖類可避免肌肉耗損，運動後補充足夠的糖與少量蛋白質就能有效增加肌肉量。本次演講內容以增加肌肉組成的生理機制為基礎，重點說明預防或治療腎臟病人肌少症的運動營養補充策略。Panel Discussion: From ICU to Community – Building a Renal Nutrition Care ContinuumPatients with acute kidney injury (AKI), especially those requiring intensive care and kidney replacement therapy, are at high risk of malnutrition, muscle wasting, and functional decline. However, nutritional care is often fragmented during the transition from acute illness to recovery and long-term kidney care. This panel will discuss strategies to establish a continuum of renal nutrition care from ICU to community, including individualized nutrition support during AKI, protein and energy management , post-AKI nutritional recovery , and multidisciplinary approaches to improve long-term outcomes and quality of life.
• Panel Discussion: From ICU to Community – Building a Renal Nutrition Care Continuum
  Shu-Tzu Chen Speaker Post-AKI Nutritional Recovery: Preventing Sarcopenia and Slowing AKI-to-CKD TransitionIt is a misconception that patients recovering from acute kidney injury should avoid a high-protein diet that may increase the risk of sarcopenia. However, this concept is not supported by current evidence. Adequate protein intake helps preserve lean body mass by reducing muscle protein breakdown, but high protein intake alone does not stimulate muscle hypertrophy. Excessive protein consumption may only increase nitrogenous waste production and impose an unnecessary metabolic burden on the recovering kidneys. The most effective strategy for increasing muscle mass is resistance exercise combined with appropriate nutritional supplement. Carbohydrate intake before exercise helps reduce muscle protein breakdown, while adequate carbohydrate with a small amount of protein after exercise effectively stimulates muscle protein synthesis and promotes muscle growth. This lecture will review the physiological mechanisms underlying skeletal muscle hypertrophy and discuss evidence-based exercise and nutritional strategies for the prevention and treatment of sarcopenia in patients with kidney disease, with particular emphasis on those recovering from acute kidney injury. 若需中文摘要 如下 急性腎損傷恢復期的病人不適合攝取高蛋白質飲食可能導致肌少症發生是錯誤的觀念，因為增加蛋白質攝取才能增加肌肉量避免肌少症發生並不正確。足夠的蛋白質可避免肌肉分解，但不會增加肌肉量。增加肌肉量不需要大量的蛋白質，過多的蛋白質只會產生較多的含氮廢物增加腎臟負擔。增加肌肉量需要阻力運動與運動前、後正確的營養補充;運動前補充糖類可避免肌肉耗損，運動後補充足夠的糖與少量蛋白質就能有效增加肌肉量。本次演講內容以增加肌肉組成的生理機制為基礎，重點說明預防或治療腎臟病人肌少症的運動營養補充策略。Panel Discussion: From ICU to Community – Building a Renal Nutrition Care ContinuumPatients with acute kidney injury (AKI), especially those requiring intensive care and kidney replacement therapy, are at high risk of malnutrition, muscle wasting, and functional decline. However, nutritional care is often fragmented during the transition from acute illness to recovery and long-term kidney care. This panel will discuss strategies to establish a continuum of renal nutrition care from ICU to community, including individualized nutrition support during AKI, protein and energy management , post-AKI nutritional recovery , and multidisciplinary approaches to improve long-term outcomes and quality of life.

• Does Mild to Moderate AKI Actually Cause CKD?
  Chi-yuan Hsu Speaker Targeting Persistent AKI and Promoting RecoveryDoes Mild to Moderate AKI Actually Cause CKD?
• Social Determinants of Health and Acute Kidney Injury
  Rolando Claure-Del Granado Speaker Practical Steps to Train (and Become) an AI-Era PhysicianPrecision Solute Control and Dynamic Dosing with CRRTSocial Determinants of Health and Acute Kidney Injury
• Pregnancy-Associated AKI: an Unmet Need(TBC)
  Raj Chakravarthi Speaker Pregnancy-Associated AKIManaging the Heart Failure Patient With Worsening Renal Function (WRF)

• The Missing Link: Navigating the Acute Kidney Disease (AKD) Window and Preventing CKD
  Jei-Wen Chang Speaker The Missing Link: Navigating the Acute Kidney Disease (AKD) Window and Preventing CKD

  Shotaro Matsumoto Moderator The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
• Spotlight on Neonatal AKI: The AWAKEN Criteria, Unique Phenotypes, and Genetic Insights
  Chih-Chia Chen Speaker Spotlight on Neonatal AKI: The AWAKEN Criteria, Unique Phenotypes, and Genetic Insights

  Shotaro Matsumoto Moderator The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
• The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in Pediatrics
  Shotaro Matsumoto Speaker The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription

  Min-Hua Tseng Moderator
• Beyond Renal Replacement: Advanced Extracorporeal Blood Purification in Pediatric Sepsis
  I-Jung Tsai Speaker Beyond Renal Replacement: Advanced Extracorporeal Blood Purification in Pediatric Sepsis

  Min-Hua Tseng Moderator
• Q&A

• Opening
• Targeted Polymyxin B Hemadsorption in Sepsis: Lessons from Japanese Experience and Patient Selection
  Kent Doi Speaker Organ crosstalk in AKITargeted Polymyxin B Hemadsorption in Sepsis: Lessons from Japanese Experience and Patient Selection
• From Guidelines to Bayesian Trials: How Should We Interpret Polymyxin B Hemoadsorption in Sepsis?
  Yen-Ta Huang Speaker From Guidelines to Bayesian Trials: How Should We Interpret Polymyxin B Hemoadsorption in Sepsis?Polymyxin B hemoadsorption has occupied an unusually contested place in sepsis care, and the way authoritative bodies describe it has shifted over time. This talk traces that evolution—from the 2020 Taiwan AKI consensus through the 2021 and 2026 Surviving Sepsis Campaign guidelines—and uses the changing recommendations as a lens on the methodological debates that underlie them. From an evidence-based medicine standpoint, the controversy is less about the device than about how we generate and grade evidence. I will first examine the frequentist evidence base, including our network meta-analysis of blood purification therapies for severe infection and sepsis/septic shock published in Critical Care Medicine. I will outline what a network meta-analysis adds—coherent ranking across multiple modalities, indirect comparison, and explicit quantification of heterogeneity—while being candid about its limitations, including reliance on the transitivity assumption, sparse networks, and the fragility of mortality estimates pooled from heterogeneous trials. I will then turn to the recently reported TIGRIS trial, which used a Bayesian, enrichment-based phase 3 design with prespecified borrowing from the EUPHRATES treatable cohort. I will highlight the strengths of the Bayesian presentation—direct posterior probabilities of benefit, transparent incorporation of prior evidence, and efficiency in a rare, mechanistically defined phenotype—alongside the cautions it demands: sensitivity to prior choice, the open-label design, and the gap between a high posterior probability and a confirmed effect. Bringing these strands together, the talk offers a multifaceted, methodology-driven reading of polymyxin B hemoadsorption in sepsis, and a transferable framework for clinicians facing the increasingly common situation in which guidelines, frequentist syntheses, and Bayesian trials appear to diverge.
• Q&A

• Personalized Fluid Management with CRRT
  Nuttha Lumlertgul Speaker Solution and Fluid BalanceUtility of Lung Ultrasound, VEXUS and Bioimpedance Analysis in Volume Assessment During RRT Personalized Fluid Management with CRRT

  Ravindra Mehta Speaker

• Station 1 The Critical Initiation: Circuit Priming & Hemodynamic Management
  Ting-Yuan Chang Speaker
• Station 2 Core Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
  Shotaro Matsumoto Speaker The Ultimate Support: Heart-Lung-Kidney Crosstalk and ECMO-CRRT Integration in PediatricsCore Decisions: Modality Selection (CVVH / CVVHD / CVVHDF) & Prescription
• Station 3 The Perfect Balance: Regional Citrate Anticoagulation (RCA) in Practice
  Hou-Xaun Emma Huang Speaker
• Station 4 Advanced Purification: Therapeutic Plasma Exchange (TPE) Concepts & Challenges
  Jhao-Jhuang Ding Speaker Advanced Purification: Therapeutic Plasma Exchange (TPE) Concepts & Challenges

• Managing the Heart Failure Patient With Worsening Renal Function (WRF)
  Claudio Ronco Speaker Hemoadsorption in the ICUSpecial lecture: 50 years of CRRT: a journey through innovationRole of Renal Functional Reserve on AKI risk and RecoveryHow do I use Hemadsorption in My PracticeManaging the Heart Failure Patient With Worsening Renal Function (WRF)

  Raj Chakravarthi Speaker Pregnancy-Associated AKIManaging the Heart Failure Patient With Worsening Renal Function (WRF)

• Adapting CRRT for Patients with Electrolyte and ACID-Base Disorders
  John Prowle Speaker Trajectories of Critical Illness – Defining Endotypes from Routine DataDynamic Prescription of CRRT Ready for Prime TimeAdapting CRRT for patients with Electrolyte and acid-base disordersExtracorporeal Therapies in Trauma, Burns and Cerebral Edema

  Lui Forni Speaker Sepsis Associated AKIBicarbonate therapy for AKI or Bicarbonate in AKI: Use and MisuseAdapting CRRT for Patients with Electrolyte and Acid-Base Disorders

• Clinical Support Information with Generative AI: Content Generation and Evaluation
  Yu-Chang YEH Speaker
• AI-Assisted Reference Management and Graphical Abstract Creation
  Yu-Chen Chuang Speaker AI-Assisted Reference Management and Graphical Abstract Creation

• SGLT-2 抑制劑於慢性腎臟病之臨床應用與保護機轉
  Chung-Kuan Wu Speaker SGLT-2 抑制劑於慢性腎臟病之臨床應用與保護機轉
• GLP-1 受體促效劑在腎臟與心血管代謝保護的新進展
  Ming-Tso Yen Speaker
• 新型鉀離子結合劑 Lokelma 的應用
  Kuang-Yu Wei Speaker 新型鉀離子結合劑 Lokelma 的應用

• AKD Care Redefined: Diabetes, Hypertension, and Strategies for Long-Term Health
  VinCent Wu Speaker
• Drug Exposures: Concerns in Kidney Safety (PPI vs Potassium-Competitive ACID Blockers (P-CABs))
  Kyungho Lee Speaker
• Acute PD vs Acute HD: Which Is the Right Choice? or Tropical Nephrology: Leptospirosis, Dengue, Malaria
  Nattachai Srisawat Speaker Precision Sepsis-AKI — Biomarkers, AI and Phenotyping in the Asia-PacificTiming of DialysisAcute PD vs Acute HD: Which Is the Right Choice?
• Tackling Heterogeneity: Phenotyping for Hemadsorption or Defining What Matters in AKI Trials: Heterogeneity and Future Direction of Major Adverse Kidney Events
  Kent Doi Speaker Organ crosstalk in AKITargeted Polymyxin B Hemadsorption in Sepsis: Lessons from Japanese Experience and Patient Selection
• Extracorporeal Therapies in Trauma, Burns and Cerebral Edema
  John Prowle Speaker Trajectories of Critical Illness – Defining Endotypes from Routine DataDynamic Prescription of CRRT Ready for Prime TimeAdapting CRRT for patients with Electrolyte and acid-base disordersExtracorporeal Therapies in Trauma, Burns and Cerebral Edema
• Q & A